【私の読了にかかった時間】18分25秒 (128 wpm)
When pregnancy begins during a complete remission of lupus, it is associated with a relatively low incidence of relapse. In contrast, relapse is more frequent among patients who have active disease at the time of conception, and in these patients the clinical course is often hectic and the reactivation of disease is sometimes associated with irreversible organ failure.
In pregnant patients with lupus, an increase in C3a is often accompanied by a decline in total C3 and total complement.
- In 92 percent of cases, preeclampsia occurs after the 32nd week of gestation, and 75 percent of patients in whom it develops are primigravidas.
- Flare-ups of systemic lupus are relatively frequent in the peripartum and postpartum periods.
- The combination of fever and lung infiltration in an immunocompromised host made histologic diagnosis obligatory. The decision to proceed with bronchoalveolar lavage and, if necessary, a lung biopsy seems rational.